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maintain a reduced cellular environment (維持一個還原性的細胞環境)
de novo synthesis (從頭合成)
de novo synthesis (從頭合成)
maintain a reduced cellular environment (維持一個還原性的細胞環境)
maintain a reduced cellular environment (維持一個還原性的細胞環境)
Its de novo and salvage synthesis serves to maintain a reduced cellular environment and the tripeptide is a co-factor for many cytoplasmic enzymes and may also act as an important post-translational modification in a number of cellular proteins. (其從頭合成與補救合成途徑有助於維持一個還原性的細胞環境，且這種三胜肽是許多細胞質酵素的協同因子，也可能在許多細胞蛋白質中充當重要的翻譯後修飾。)
redox sensing
redox
regulation
氧化還原的調節，氧化還原調節
redox regulation (氧化還原的調節，氧化還原調節)
氧化還原的調節，氧化還原調節 (redox regulation)
Endogenous glutathione adducts
內源性的穀胱甘肽加合物
Endogenous glutathione adducts (內源性的穀胱甘肽加合物)
內源性的穀胱甘肽加合物 (Endogenous
glutathione adducts)
#
Source or References (資訊來源或是參考的資訊):
https://pubmed.ncbi.nlm.nih.gov/17168687/
Info cited on 2023-02-24-WD5 (資訊引用於 中華民國112年西元2023年2月24日) by 湯偉晉 (WeiJin Tang)
#
Abnormalities of hydrogen sulfide and glutathione pathways in mitochondrial dysfunction PY2021 IR95 cysteine, sulfur
https://www.sciencedirect.com/science/article/pii/S2090123220300643
##
Fig. 2. Transsulfuration and H2S oxidation pathways. In the transsulfuration pathway (in orange), the enzymes cystathionine β-synthase (CBS) and cystationine γ-ligase (CSE) use cysteine as a substrate for the synthesis of sulfides (H2S). The same cysteine is used by glutamate cysteine ligase (GCL) for the synthesis of GSH in the glutathione pathway (not shown). In the mitochondrial H2S oxidation (in red), sulfide-quinone oxidoreductase (SQR) converts sulfide into thiosulfate by transferring two electrons from H2S to CoQ. Thiosulfate is then converted into sulfite by thiosulfate sulfurtransferase (TST) and persulfide dioxygenase (ETHE1), a reaction that requires glutathione (GSH) as an electron acceptor. Excess sulfite is converted into sulfate by sulfite oxidase (SUOX). 3-MP = 3-mercaptopyruvate, 3-MST = 3-mercaptopyruvate sulfurtransferase, CoQ Ox = Coenzyme Q oxidized, CoQRed = Coenzyme Q reduced.
##
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differential
diagnosis
鑑別診斷
differential diagnosis (鑑別診斷)
鑑別診斷 (differential
diagnosis)
| 法規名稱： | 藥品生體可用率及生體相等性試驗作業準則 EN |
|---|---|
| 修正日期： | 民國 109 年 06 月 11 日 |
| 法規類別： | 行政 ＞ 衛生福利部 ＞ 食品藥物管理目 |
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