glutathione peroxidase

glutathione peroxidase

glutathione peroxidase (GPx)

glutathione peroxidases (GPx) family

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glutathione peroxidases (GPx) family

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Throughout evolution, heme peroxidases, similar to myeloperoxidase (MPO), LPO, salivary peroxidase (SPO), and thyroid peroxidase (TPO), were found to be key enzymes for modulating the OS process in the cytoplasmic and secretory fluids (Davies et al., 2008). Antioxidants or free radical scavengers are incorporated into the innate immune arsenal, hormone synthesis and exocrine secretions, generating ROS with antimicrobial actions and counterbalancing the actions of other OS-related enzymes, including the glutathione peroxidases (GPx) family (Morrison and Allen 1966; Petrides and Nauseef 2000; Ihalin et al., 2006; Davies et al., 2008). Recently, a family of six protein isoforms called peroxiredoxins was described, and their structure and function associated with OS were further detailed (Rhee et al., 2012).

As a disease mediator, GPx levels and ROS accumulation have been identified as biomarkers and implicated in the protective mechanisms and damage triggered by the LFU (Wakamatsu et al., 2008).

資訊來源：

Oxidative Stress in the Protection and Injury of the Lacrimal Gland and the Ocular Surface: are There Perspectives for Therapeutics PY2022 IR95 Glutathione 教材

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資訊來源：

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Placeholder 湯偉晉編寫的英文字典

Placeholder 湯偉晉編寫的英文字典