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湯偉晉 (WeiJin Tang) 編寫的字典 (電子郵件: WeiJin.Tang@gmail.com)(行動電話:0958-227-243)(在社群軟體LINE上面的ID:WeiJin.Tang)(在社群軟體 微信WeChat 上面的ID:WeiJin_Tang)(在社群軟體 Skype 上面的ID:WeiJin.Tang) English-Chinese Online Dictionary,英文-中文 線上字典(詞典),中英字典,英中字典,中英文字典, English Dictionary by WeiJin Tang (湯偉晉 編寫的英文字典)
Start a short learning session in response to something truly worth learning.(為值得學習的事物展開一段簡短的學習之旅。)
Start a short learning session in response to something truly worth learning.
為值得學習的事物展開一段簡短的學習之旅。
小品文_湯偉晉寫的小品文_2025-0422_簡短的學習之旅_
中華民國114年
西元2025年4月22日星期二
Start a short learning session in response to something truly worth learning.
為值得學習的事物展開一段簡短的學習之旅。
湯偉晉 親筆寫於
中華民國114年4月22日
星期二台北時間上午6點05分
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red flag (紅旗警示)
red flag (紅旗警示)
「red flag」在英文中的意思:
在英文對話或文章中,“red flag” 是一個慣用語,源自於賽車或軍事中的紅旗警示,比喻某件事情是警訊、警告、危險的徵兆。它常用來表示某個行為、情況、或特徵可能預示著將來會出現更大的問題。
英文例句:
That he never takes responsibility for his mistakes is a major red flag in a relationship.
他從不為自己的錯誤負責,這在一段感情中是一個很大的警訊。
The job posting mentioned "must be willing to work under pressure for extended hours" — that’s a red flag for potential overwork.
這份職缺提到「必須願意在壓力下長時間工作」——這可能是過勞的警訊。
If a new startup has no clear business model, that’s a red flag for investors.
如果一家新創公司沒有明確的商業模式,對投資人來說就是一個警訊。
(中文由 ChatGPT 負責翻譯)
monomer (單體)
dimer (二聚體)
trimer (三聚體)
tetramer (四聚體)
multimer (多聚體)
monomer (單體)
dimer (二聚體)
trimer (三聚體)
tetramer (四聚體)
multimer (多聚體)
monomer (單體)
dimer (二聚體)
trimer (三聚體)
tetramer (四聚體)
multimer (多聚體)
monomer (單體)
dimer (二聚體)
trimer (三聚體)
tetramer (四聚體)
multimer (多聚體)
monomer (單體)
dimer (二聚體)
trimer (三聚體)
tetramer (四聚體)
multimer (多聚體)
monomer (單體)
dimer (二聚體)
trimer (三聚體)
tetramer (四聚體)
multimer (多聚體)
論文摘要 蛋白質四級結構複合物在細胞中多聚體結構各自扮演不同重要角色,像是具有二聚體結構的轉錄因子參與著基因調控,而三聚體結構的病毒感染相關醣蛋白則與人類免疫系統缺陷病毒相關,因此若能分類蛋白質四級結構複合物,對於後基因體時代的蛋白質體學研究是有相當大的幫助。現今針對研究單體與多聚體序列的預測系統並不普遍。因此,本研究設計兩層機器學習的架構,發展蛋白質四級結構複合物分類預測系統PClass。將蛋白質四級結構複合物分為五類包括單體、二聚體、三聚體、四聚體及其他亞基類,第一層在拔靴法架構下配合support vector machine提出新的模型選擇方法,每類複合物以序列組成、entropy及accessible surface area 之特徵編碼,產生多個特徵模組透過評估的方式挑選效能最佳模型作為每類複合物的特徵模組,準確度可以達到馬修斯相關係數70%以上。接著第二層的建構結合了第一層特徵模組進行整合機制並利用六種機器學習方法改善預測效能,使得每類複合物預測準確度皆能提升10%以上。最後,以二聚體結構的轉錄因子與三聚體結構的病毒感染相關醣蛋白實際驗證預測系統。 | |
論文外文摘要 Protein quaternary structure complex is also known multimer, which plays an important role in the cell. Such as dimer structure of the transcription factor involved in gene regulation, but trimer structure of the virus infection associated glycoprotein is related to the system with the human immunodeficiency virus. Therefore, if we can classification the protein quaternary structure complex for post genome era of proteomics research is of great help. Nowadays, the classification systems among protein quaternary structures have not been widely developed yet, therefore, in this study, we designed the architecture of the two layer machine learning and developed the classification system, PClass. Protein quaternary structure of the complex is divided into five categories, including monomer, dimer, trimer, tetramer and other subunits class. The first layer in the framework of the bootstrap method with support vector machine to propose a new model selection method, each type of complex according to sequences, entropy and accessible surface area as the feature encoding, generating a plurality of feature models and through the evaluation way to select the optimal model of effectiveness as each kind of complex feature model. In this stage, the best performance can reach as high as 70% of MCC. Then the second layer construction combines the first layer model to integrate mechanisms and use of six machine learning methods to improve the prediction performance, this system can be improved over 10% in MCC. Finally, we analyzed the performance of our classification system by transcription factor in dimer structure and virus infection associated glycoprotein in trimer structure. |
RayShine Photonics (銳陽光電)
RayShine Photonics Corporation (銳陽光電股份有限公司)
RayShine Photonics (銳陽光電)
RayShine Photonics Corporation (銳陽光電股份有限公司)
RayShine Photonics (銳陽光電)
RayShine Photonics Corporation (銳陽光電股份有限公司)
王仁宏 董事長先生
RayShine Photonics (銳陽光電)
RayShine Photonics Corporation (銳陽光電股份有限公司)
Manganese transporter (錳離子轉運蛋白)
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Manganese transporter (錳離子轉運蛋白)
To date, three key Mn transporters, including SLC39A8, SLC39A14 and SLC30A10, have been identified and functionally characterized as causal mutations in Mn-related human inherited diseases and in several model organisms.
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